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Study: Identifying ingredients supporting a "microbiome-friendly" claim

ReportsBeauty & Personal Care

A study conducted in partnership with BYOME LABS

The skin microbiome is now a key focus in skincare, with consumers embracing a holistic approach that supports skin health at its root. This fast-growing trend is driving innovation across beauty categories. In response, IMCD Beauty & Personal Care and BYOME LABS have conducted a study to evaluate how specific cosmetic ingredients interact with the skin’s microbiome composition.


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Which ingredients have been tested?

We tested the impact of ingredients widely recognized for their anti-aging and hydrating properties: Sodium Hyaluronate*, Ascorbyl Tetraisopalmitate* and Glycerin.

How have these ingredients been tested?

They have been tested alone and in formulation on 9 major strains via BYOME LAB's in-vitro biofilm testing methodology. Products have been applied on biofilms and strains variations have been measured after 4 hours of incubation.

Other ingredients composing the formulation (preservative, emollient (Caprylic/Capric Triglyceride*) and emulsifier (Batyl Alcohol, Caprylic/Capric Triglyceride, Lecithin, Stearic Acid, Tocopherol*)) as well as the formulation base itself, have also been tested to check their behavior towards the skin microbiome.
All ingredients have been tested at their usual concentrations in cosmetic products.

*These ingredients are part of IMCD portfolio and are subject to country-specific availability. Check which ones are available in your country in the "Related Products" box!

Which microorganisms have been studied?

Our 9 selected strains fall into 4 key groups of microorganisms:

  • Staphylococcus genus: This group includes Staphylococcus epidermidis, a beneficial species known to stimulate keratinocyte renewal and boost ceramide production. Staphylococci are key players in the skin’s barrier and immune defense.
  • Cutibacterium genus: This group includes Cutibacterium acnes, a microbe famous for its role in sebum metabolism and maintaining skin pH. Certain strains are linked to acne, while others may help keep skin balanced.
  • Corynebacterium genus: Like staphylococci, these bacteria contribute to the skin’s protective ecosystem and help maintain its natural balance.
  • Malassezia genus: A genus of yeasts that influences skin pH. While part of the normal flora, some species are associated with conditions such as atopic dermatitis or seborrheic dermatitis.
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About BYOME LABS
BYOME LABS is a pioneering French deeptech startup specialising in microbiome science for cosmetics, dermocosmetics and pharma.
With over 20 years of cumulative expertise in skin, scalp, oral, and vaginal microbiomes, the company brings together leading experts in microbiology, immunology, genetic engineering, and artificial intelligence.
Through advanced in vitro testing, expertise in biofilm microbiology, and AI-powered tools like the instant microbiome-testing tool BYOME DERMA, the team bridges cutting-edge research and industrial innovation to enable personalised, microbiome-respecting skincare.
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Study: Identifying ingredients supporting a "microbiome-friendly" claim | IMCD Denmark